ALEXANDRA PERDIGÃO MAIA DE SOUZA
Título da Dissertação: EXPOSURE ASSESSMENT OF SOUTHERN BRAZIL POPULATION TO DEOXYNIVALENOL THROUGH THE CONSUMPTION OF WHEAT-BASED FOOD PRODUCTS
Orientadora: Prof. Dr. Miguel Machinski Junior
Data da Defesa: 30/06/2016
RESUMO GERAL
Wheat is widely used in human food products and accounts for approximately 30 % of world grain production. However, the grain can become contaminated by the trichothecene-producing Fusarium, with deoxynivalenol (DON) being the most commonly found in foods. Therefore, the aim of the present study was to determine the occurrence of this mycotoxin in commercialized wheat flours and to estimate the exposure of the population to DON by consumption of wheat-based products in the city of Maringá, Brazil. A total of 81 samples of wheat flour were analyzed, 75 (92.6 %) samples were positive for DON, containing a mean level of 133.19 ± 7.99 μg kg-1. None of the samples exceeded the tolerated maximum limit regulated by Brazilian and European legislation. Average Probable Daily Intake (APDI) by consumer of wheat flour was 0.17 μg kg-1 body weight day-1, representing 17 % of Provisional Maximum Tolerable Daily Intake (PMTDI). Maximum Probable Daily Intake (MPDI) of a high consumer of wheat flour was 0.65 μg kg-1 body weight day-1, representing 65 % of PMTDI. The exposure assessment showed that there is low risk to the health of the population exposed to DON in wheat-based food products commercialized in Brazil.
Keywords: Deoxynivalenol; Trichothecenes; Exposure assessment; Food safety; Wheat-based products
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